|
KMID : 0360220130540030443
|
|
Journal of the Korean Ophthalmological Society
2013 Volume.54 No. 3 p.443 ~ p.448
|
|
|
Combined Anti-VEGF and C3F8 Injection for Large Submacular Hemorrhage Secondary to Age-Related Macular Degeneration
|
|
Lee Min-Young
Seo Won-Moon
Choi Yul-Je
|
|
|
Abstract
|
|
|
|
Purpose: To evaluate the effect of intravitreal expansile gas (C3F8) with anti-VEGF injection for the treatment of large submacular hemorrhage (SMH) secondary to age-related macular degeneration (ARMD). Methods: In this report, 18 eyes of 18 patients with large SMH secondary to ARMD were treated with a simultaneous injection of 0.3 cc C3F8 and 0.05 ml anti-VEGF intravitrealy. Results: The mean age was 64.89 ± 5.68 years and the mean size of SMH was 4.44 ± 1.25 disc diameters (DD). The minimum follow-up period was 12 months (range: 12-17 months). Mean preoperative best corrected visual acuity (BCVA) was 1.72 ± 0.56 log MAR which improved significantly to 1.01 ± 0.68 log MAR at 12 months (p = 0.002). SMH displacement occurred in all eyes. BCVA improved 2 or more lines in 11 eyes (61.1%) and deteriorated in 1 eye (5.6%). Conclusions: In this report, intravitreal injection of an expansible gas (C3F8) with anti-VEGF produced successful results in anatomical displacement of SMH and early visual improvement.
|
|
|
KEYWORD
|
|
|
Age-related macular degeneration, Anti-VEGF, C3F8 gas, Submacular hemorrhage
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|